Do exogenous oestrogens and progesterone influence asthma?

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Occasional reviews Do exogenous oestrogens and progesterone influence asthma?

Between 20% and 40% of women of childbearing age in the UK use hormonal contraceptives. 2 In a survey carried out in Oxfordshire in 1990 about 20% of women aged 45–64 years were taking hormone replacement therapy (HRT). Around 5% of women of childbearing age in the UK have diagnosed asthma, and a higher proportion have asthmalike symptoms. There is less information available about the prevalenc...

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Do hormonal contraceptives influence asthma severity?

There is some evidence that endogenous progesterone and oestrogen levels influence asthma severity in females, but little is known about the effects of hormonal contraceptives. This study aimed to describe how females with asthma perceived the effects of hormonal contraceptives on symptom severity, and to describe the association between asthma severity and current use of hormonal contraceptive...

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Do dietary phytoestrogens influence susceptibility to hormone-dependent cancer by disrupting the metabolism of endogenous oestrogens?

Phytoestrogens are natural constituents of our diets that have been suggested to protect against hormone-dependent breast cancer. Some of the diverse effects of these compounds may be attributed to ligand-dependent differences in their interaction with oestrogen receptor sub-classes. However, phytoestrogens can also inhibit enzymes that are involved in the generation and removal of endogenous s...

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Do Grandmaternal Smoking Patterns Influence the Etiology of Childhood Asthma?

BACKGROUND Animal data suggest that tobacco smoke exposure of a mother when she is in utero influences DNA methylation patterns in her offspring and that there is an effect on the respiratory system, particularly airway responsiveness. The only study, to our knowledge, in humans suggests that there is a similar effect on asthma. The present study tests whether an association with respiratory pr...

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Relationship between concentrations of maternal plasma oestrogens and progesterone and response to artificial rupture of membranes.

The concentrations of oestradiol-17beta, oestriol, and progesterone were measured in the plasma of 100 patients at the time of induction of labour by artificial rupture of membranes. There was no statistically significant difference in the hormone concentration or in the ratio of oestrogens to progesterone between patients who went into labour after rupture of the membranes and those who did no...

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ژورنال

عنوان ژورنال: Thorax

سال: 1999

ISSN: 0040-6376

DOI: 10.1136/thx.54.3.265